An in-depth guide is available here, written by Feeds.
Prayer
Prayeris a skill which grants the player specialized buffs in combat. All players start with limited access to the Prayer skill. As one's Prayer level increases, they gain access to new prayers. As players traverse the land and complete many adventures, they find themselves presented with the opportunity to gain the prayers and blessings.
Tips / Bonuses
By combining the curses prayer Soulsplit and the Ice Katana, You can make a pretty deadly combo that will prevent death always making sure you have 1 hp at the bare minimum.
Bones
Types of Bones
Phoenix Bones
Icy Skeleton Bones
Frost Dragon Bones
Dagannoth Bones
Dragon Bones
Penguin Bones
Big Bones
Bones
Experience
Bones
Type
Normal EXP
Hardcore / Iron-Man EXP
Normal Bones
1,650
330
Big Bones
490
98
Penguin Bones
14,850
2,970
Dragon Bones
2,375
474
Dagannoth Bones
4,120
824
Frost Dragon Bones
19,800
3,960
Icy Bones
50,000
10,000
Phoenix Bones
75,000
15,000
Ancient Curses
Curses can be accessed through the altar at ::home. Which can be found to the right of the bank, near where you can see a mining icon.
Training
A player can train the prayer skill in multiple ways. For basics, a player can bury bones for some experience. However, there is an altar at ::home that you can use your bones on to gain quicker experience. It is recommended to use frost dragon bones. Frost dragon bones can be received from players, ::frosts, and other areas around Dreamscape.
For gaining faster EXP, it's smart to put on a Double XP Ring. It gives you double experience in the skill. You can gain a Double XP Ring as a loot from a mystery box or from donating.
Important :
You can stack the exp rates using both the altar and Double XP Ring!